Steroids and derivatives
Apexbio Technology LLC PYRAZINAMIDE-D3-1MG
Pyrazinamide-d3 (CAS No 1432059-16-9) is a deuterium-labeled derivative used in biomedical research as a stable isotope for various studies Originating from antimicrobial research it is primarily utilized to investigate Mycobacterium tuberculosis the causative agent of tuberculosis Pyrazinamide-d3 acts by disrupting the bacterial membrane potential and interfering with fatty acid synthase I which is critical for the bacterium s survival and replication In vitro studies frequently demonstrate its activity in the nanomolar to low micromolar range making it effective for precise quantitative analysis This compound is commonly applied in cell models animal studies and drug screening assays to measure drug metabolism and pharmacokinetics Experimental concentrations typically depend on the specific research design allowing for flexibility across various experimental frameworks ultimately aiding in the development of novel therapeutics against bacterial infections
eMolecules 58050-55-8 | Medchem Express | 24 25-Dihydroxy VD2 | 1mg | 446271510 | HY-76801 | 428.657 | C28H44O3
Medchem Express | 24 25-Dihydroxy VD2 | 1mg | 446271510 | HY-76801 | 58050-55-8 | 428.657 | C28H44O3
Cayman Chemical Resolvin D2 Neurochemicals
A product of the action of 15- and 5-LO on DHA; dampens excessive neutrophil trafficking to sites of inflammation; reduces zymosan-stimulated PMN infiltration by 70% at 10 pg per mouse; reduces PAF-stimulated leukocyte adherence and emigration at 1 nM; stimulates nitric oxide production decreases leukocyte-endothelial interactions; reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance in a mouse model of sepsis
Cayman Chemical LnolIn VItamIn D3 5g
A biologically inactive precursor to calcitriol converted to active metabolites in vivo; obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol to previtamin D3 by UVB radiation, followed by isomerization to vitamin D3; can be converted to 25-hydroxy vitamin D3 in the liver by CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney
TARGETMOL CHEMICALS INC 5-6-TRANS-VITAMIN D3 5MG
Also available in 1mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. 56-trans-Vitamin D3（56-trans-Cholecalciferol） is an isoform of Vitamin D3 which is converted from Vitamin D3 on the skin surface after light exposure. purity: 97%
Medchemexpress LLC Alogliptin-d3 | 1133421-35-8 | 99.6% | C18H18D3N5O2 | 5 MG
Alogliptin-d3 is the deuterium labeled Alogliptin, a potent, selective, and orally active inhibitor of DPP-4 with an IC50 of <10 nM. It exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9 and can be used for the research of type 2 diabetes. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for quantitation during drug development and can influence pharmacokinetic and metabolic profiles.
- Deuterium labeled Alogliptin.
- Potent, selective, and orally active inhibitor of DPP-4.
- Exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
- Suitable for research of type 2 diabetes.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cayman Chemical 25hydroxy VItamIn D3 3 3am 1mg
A vitamin D3 analog; contains a highly reactive amine group that can be coupled to a sepharose matrix for affinity purification of vitamin D binding protein; inhibits 25-hydroxy vitamin D3-1α-hydroxylase
MOLECULAR DEPOT LLC 25-OH Vitamin D3 Biotin - 1 mg
25-OH Vitamin D3 Biotin Conjugate consists of 25-OH Vitamin D3 conjugated to Biotin via a 22 A spacer arm The spacer adds flexibility to the 25-OH Vitamin D3 moiety which is required for its interaction with specific antibodies and other binding partners This compound has been tested for use in several 25-OH Vitamin D applications including ELISA The conjugate is supplied as a DMSO stock solution For in vitro research use only
Medchemexpress LLC β-Estradiol 17-hemisuccinate | 7698-93-3 | 98.8% | 372.45 | 1 MG
β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol, classified as a drug derivative. It is intended for research applications.
- Synthetic derivative of estradiol
- Molecular formula: C22H28O5
- Molecular weight: 372.45
- Purity: 98.83% (LCMS)
- Appearance: White to off-white solid
- Storage: 4°C, stored under nitrogen
- Storage in solvent: -80°C for 6 months; -20°C for 1 month (stored under nitrogen)